RAF Typhoon FGR4s have conducted a mission with France's air force in a coordinated attack against an hidden munitions depot in Syrian territory operated by the IS group, as stated by the UK's MoD.
The location, identified by intelligence, was thought to be housing weapons and explosive materials, the statement said, and was located in mountainous terrain just north of the ancient city of Palmyra in central Syria.
"Our aircraft employed precision-guided Paveway IV munitions to hit a number of entry passages providing entry to the depot... preliminary assessments are that the objective was successfully hit," officials stated.
There was no indication of any harm to civilians in the operation late on Saturday and all the aircraft returned to base without incident, the MoD added.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as the so-called Islamic State - established militant control over large swathes of both Syria and Iraq until 2019.
"This operation shows British leadership, and determination to work closely with our partners, to eliminate any resurgence of Daesh and their dangerous and violent ideologies in the region," UK Defence Secretary John Healey remarked.
UK warplanes have carried out surveillance missions over Syrian airspace to "forestall any attempted resurgence" of Islamic State subsequent to its routing at the battle of Baghuz in the year 2019, the ministry said.
"I must thank the personnel of our armed forces involved in this operation for their expertise and their bravery," Healey added. "They were among thousands of UK service members stationed over the holidays. This action, to eliminate militants who pose a risk to our way of life, highlights how our armed forces are ready to step up, continuously, protecting the UK at home and influential overseas."
Last December, the United States armed forces conducted what it called a "major assault" on IS targets in Syria, after an assault killed two US servicemembers and a local interpreter in the Palmyra area.
The U.N. says Daesh still has roughly 5-7 thousand militants in Syria and Iraq.
